HS1CAS12A AND EV1CAS12A CONFER EFFICIENT GENOME EDITING IN PLANTS

Hs1Cas12a and Ev1Cas12a confer efficient genome editing in plants

Cas12a, also known as Cpf1, is a highly versatile CRISPR-Cas enzyme that has been widely used in genome editing.Unlike its well-known counterpart, Cas9, Cas12a has unique features that make it a VIP Series Round Liner highly efficient genome editing tool at AT-rich genomic regions.To enrich the CRISPR-Cas12a plant genome editing toolbox, we explore

read more

Environmental optimization of warm mix asphalt (WMA) design with recycled concrete aggregates (RCA) inclusion through artificial intelligence (AI) techniques

Warm Mix Asphalts (WMAs) are asphalt concretes produced at lower temperatures than traditional Hot Mix Asphalts (HMAs).Nonetheless, the above is not enough to diminish the environmental impacts associated with the road infrastructure industry.Accordingly, incorporating Recycled Concrete Aggregate (RCA) as a partial replacement for Natural Aggregate

read more

Rare disease narratives on social media: A content analysis

Purpose: Social media provides an opportunity for the expression of people with rare conditions and may provide valuable insight into lived experiences to inform genomic care.Our objective was to describe the nature and content of rare disease video narratives on social media.Methods: We reviewed content on a short-video-format social media website

read more